The Power of Glean and Prisma AIRS Integration

Feb 05, 2026
4 minutes

Accelerating Secure AI Adoption

The rapid adoption of AI is transforming the enterprise, unlocking unprecedented productivity and accelerating workflows at a record pace. However, this velocity creates a new productivity paradox: The faster AI moves, the more it can expose the organization to entirely new categories of risk. Without specialized guardrails, unchecked AI can inadvertently bypass company policies, violate legal standards, or ignore ethical norms.

To bridge this gap, Glean, the Work AI platform, and Palo Alto Networks Prisma® AIRS™ have integrated to provide an essential security layer that empowers organizations to adopt generative AI with confidence, helping ensure that massive productivity gains never come at the cost of trust, security or compliance.

How Glean and Prisma AIRS work together.
Glean and Prisma AIRS stop AI attacks in runtime.
Display of how a prompt injection is blocked by a Work AI assistant.
Prompt injection threat blocked in real time.

Real-Time Defense Against the Modern AI Threat Surface

Generic filters often fail to catch the sophisticated nuances of AI-driven attacks. The integration of Glean and Prisma AIRS provides a purpose-built defense that acts in real time across three critical areas:

1. Neutralizing Prompt Injection

Prompt injections are malicious instructions designed to trick AI models into ignoring their safety protocols, potentially leading to the exposure of sensitive data or the execution of unauthorized actions.

For instance, an attacker could craft a prompt that causes the AI to leak its own system instructions leading to data loss. Glean and Prisma AIRS instantly detect these sophisticated manipulation attempts, blocking the request and notifying the user before the organization's integrity is compromised.

2. Safeguarding Against Harmful and Toxic Content

AI interactions must remain professional, ethical and safe.

By scanning both user prompts and AI-generated responses against organizational policy, Glean and Prisma AIRS automatically block requests that contain toxic, biased, or otherwise harmful content. This enables AI to remain a positive and productive asset for the entire workforce.

3. Preventing Malicious Code and Unsafe URLs

AI models can sometimes generate unsafe code snippets, get data from a poisoned source, or provide harmful links that lead to phishing sites or malware downloads.

For example, a developer might ask an AI assistant for a code library to process data, and the model could inadvertently suggest a malicious package that compromises the application. The Glean and Palo Alto Networks integration provides a crucial safety net, inspecting all generated content for malicious patterns and preventing employees from interacting with risky URLs, keeping the entire AI-driven development and research lifecycle secure.

Secure AI in Minutes with Out of the Box Integration

The true power of the Glean and Palo Alto Networks partnership lies in its simplicity. We’ve removed the friction of complex security configurations, enabling organizations to realize value immediately through a seamless, out of the box integration.

Onboarding is completed in three simple steps within the Glean admin console:

  1. Navigate to AI Security and select Palo Alto Networks AI Runtime Security™.
  2. Paste your Prisma AIRS Runtime Security API Key.
  3. Click Save.
Glean Admin Console for AI security.
Activate Prisma AIRS from the Glean admin console.

With these three clicks, the integration is live, providing an invisible but invincible layer of defense across your AI chats and agent interactions.

AI security showing rundown of policy violation status.
Glean admin panel showcasing all findings.

Partnering for a Secure AI Future

As enterprises scale their AI initiatives, specialized security becomes non-negotiable. Prisma AIRS provides the advanced, granular protection needed to catch threats that standard vendors can often miss, and its integration with Glean delivers that protection exactly where work happens.

Drive productivity, foster innovation, and secure your future with Glean and Palo Alto Networks.

Key Takeaways

  • Real-Time Threat Mitigation: Instantly block prompt injections, toxic content, and malicious code, transforming AI from a risk factor into a secure asset.
  • Frictionless Deployment: Achieve comprehensive AI security in minutes with a simple, three-click API integration within the Glean console.
  • Time to value: Scale AI adoption across the enterprise by ensuring every interaction complies with internal policies and global safety standards.

Ready to Deploy Secure AI? To explore how this integration can protect your organization, sign up for the Glean and Palo Alto Networks upcoming webinar.


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