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Shield unpatchable legacy assets inline without invasive agents, reboots or operational downtime. Security without compromise.
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A Leader in The Forrester Wave™: OT Security Solutions, Q3 2026
The World Runs on Critical Infrastructure. We Secure it.
Stop machine-speed threats across OT, 5G and IoT
with AI-driven cyber defense.
TRUSTED BY
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Challenges
Legacy OT security tools create unmanageable operational risk.
Growth in OT, 5G and IoT devices expands the attack surface faster than fragmented tools can defend, while adversaries leverage generative and frontier AI to chain flaws at machine speed.
68%
of organizations do not have complete visibility across all connected OT assets.
55%+
report elevated costs caused by tool sprawl across legacy OT security stacks.
95%
of security leaders worry about weaponized AI targeting critical infrastructure.
Overview
The industry's most advanced critical infrastructure defense against frontier AI
When industrial operations depend on uptime, resilience requires asset-centric visibility and active inline prevention in a single platform. Neutralizing AI-driven threats across OT, 5G, IoT and legacy infrastructure demands automated threat prevention powered by operational risk prioritization.
1M+firewalls deployed
75,000+customers protected worldwide
650+OT-specific threat signatures
8 of 10top manufacturers protected
10 of 10top utilities protected
7 of 10top U.S. hospitals protected
Use Cases
End-to-end security across your entire operational footprint
Achieve active threat prevention across industrial environments, healthcare networks and cellular deployments without compromising uptime or safety.
Secure OT Infrastructure
Protect the assets, networks and remote operations that keep industrial environments running with AI-driven, proactive security.
Key capabilities
Eliminate Asset Blind Spots
Gain continuous, real-time visibility into legacy, proprietary and AI-enabled assets without adding new sensors or disrupting operations.
Prioritize Operational Risk
Weigh vulnerability severity against asset criticality and network exposure to cut alert noise and surface the risks that genuinely threaten availability.
Enforce Inline Protection
Combine asset-centric visibility with active enforcement to stop lateral movement and machine-speed attacks before they reach critical processes.
Protect Unpatchable Assets
Apply AI-driven virtual patching at the network layer to secure OT networks against weaponized frontier AI threats without requiring maintenance downtime.
Resources
Accelerate Your OT Infrastructure Security Strategy
Ready to get started?
Talk to a critical infrastructure security specialist
Assess your OT security posture, identify critical visibility gaps and map a path towards strong, simplified protection.
Talk to an expertSecure Healthcare Systems
Safeguard clinical assets and patient safety with agentless IoMT discovery, risk prioritization and virtual patching without workflow disruption.
Key capabilities
Agentless IoMT Discovery
Profile every connected medical device — from infusion pumps to imaging equipment — and reveal active clinical utilization without firmware risk or workflow disruption.
Prioritize Clinical Risk
Assess device criticality, clinical function and attack paths to cut alert noise by 90%, allowing teams to act on risk safely without consulting clinical staff for every decision.
Enforce Native Protection
Apply AI-driven virtual patching for unpatchable CVEs and block 69% more evasive command-and-control traffic inline before it reaches life-sustaining equipment.
Automate Compliance
Seamlessly integrate with clinical CMMS databases (AIMS3, Nuvolo) and generate audit-ready evidence mapped to HIPAA and NIST CSF 2.0 without manual data aggregation.
Resources
Accelerate Your Healthcare Infrastructure Security Strategy
Ready to get started?
Talk to a critical infrastructure security specialist
Assess your IoMT security posture, uncover visibility and risk gaps and strengthen protection across connected medical devices and clinical environments.
Talk to an expertSecure Enterprise 5G & LTE
Extend zero trust security across OT enterprise cellular networks with subscriber identity intelligence and inline threat prevention from edge to cloud.
Key capabilities
Hyper-Converged Edge
Combine routing, switching, SD-WAN and multiple WAN interfaces in a compact, quantum-optimized, ruggedized NGFW to secure OT and cellular access networks.
Block Machine-Speed Threats
Eliminate human-in-the-loop delay by stopping lateral movement and frontier AI attacks in real time, preventing initial access from turning into operational impact.
Enterprise 5G Security
Edge to cloud access network security eliminates policy fragmentation, inspects traffic inline at the OT layer, enabling zero trust access from 5G edge to core to AI workloads.
Ruggedized NGFWs
New security-first NGFWs are environmentally hardened to protect critical infrastructure at the extreme edge. They are fanless, IP40 rated, and shock- and vibration-certified for the most demanding locations.
Resources
Accelerate Your Enterprise 5G & LTE Security Strategy
Ready to get started?
Talk to a critical infrastructure security specialist
Assess your private 5G security posture, identify visibility and protection gaps and strengthen security across users, devices and connected infrastructure.
Talk to an expertWHAT OUR CUSTOMERS ARE SAYING
Analyst Recognition
Named a Leader. Three times over.
Resources
Accelerate Your Critical Infrastructure Security Strategy
Access analyst research, buyer’s guides and technical analyses to secure your OT, IoT and private 5G infrastructure in the frontier AI era.
Frequently Asked Questions
Traditional tools offer passive visibility and detection only, requiring manual intervention to update firewall policies. Palo Alto Networks integrates asset-centric visibility directly with active inline threat prevention in a unified architecture, automatically blocking threats at the network layer.
No. Security functions are delivered natively through the Next-Generation Firewall (NGFW) directly within the existing network path. This eliminates complex integrations while enabling real-time risk prioritization and zero-downtime virtual patching.
Yes. Our ruggedized, hyper-converged, security-first edge firewalls are equipped with integrated 5G/LTE WAN connected to a subscriber identity context (IMEI/IMSI). This provides protection across enterprise 5G environments where SPAN-based tools lack visibility.
Multifactor operational risk prioritization analyzes asset criticality, network exposure and attack paths rather than relying solely on raw CVSS scores. This eliminates up to 90% of noncritical alert noise so teams can focus on actionable threats.
Virtual patching blocks threats at the network perimeter without requiring endpoint agents, asset reboots or maintenance downtime. Threat intelligence updates are automatically delivered across the global network to protect unpatched devices.